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For academics: explore our research

For academics: explore our research

The scientific details of our current research projects.

Project Name Primary Locationsort descending Principal Investigator
Neuromuscular junctions (NMJs) as therapeutic targets in MND Aberdeen Bewick, Guy
Cardiovascular and organ pathology in spinal muscular atrophy Aberdeen Parson, Simon
Understanding the molecular pathogenesis of clinical heterogeneity in motor neuron disease Aberdeen Gregory, Jenna
High-resolution imaging of synaptic integrity in MND Dundee Henstridge, Chris
Investigating the role of TDP-43 in ALS Dundee McGurk, Leeanne
Studying myelinated axon biology using zebrafish Edinburgh Lyons, David
Centre for Biomedicine, Self and Society Edinburgh Pickersgill, Martyn
The cell and molecular biology of neurodegenerative disease Edinburgh Skehel, Paul
Modelling MND using human induced pluripotent stem cells Edinburgh Chandran, Siddharthan
Edinburgh Brain Bank Edinburgh Smith, Colin
A potential role for synapses in amyotrophic lateral sclerosis Edinburgh Spires-Jones, Tara
CARE-MND Edinburgh Pal, Suvankar
New drugs that stabilise motor axons (UK Spinal Muscular Atrophy Consortium) Edinburgh Becker, Catherina
Developing new therapies for motor neurone disease (SMA and ALS) Edinburgh Gillingwater, Tom
Signaling pathways to degeneration and resilience Edinburgh Hardingham, Giles
Cellular and molecular anatomy of the human neuromuscular junction Edinburgh Jones, Ross
Identifying novel neuroprotective mechanisms in motor neuron disease Edinburgh Murray, Lyndsay
MND-SMART Clinical Trial Edinburgh Chandran, Siddharthan
Stem cell disease modelling to investigate mechanisms of selective vulnerability of motor neurons Edinburgh Selvaraj, Bhuvaneish T
Elucidating RNA metabolism changes underlying the progressive neural cell biology of ALS Edinburgh Sibley, Chris
Advancing drug discovery through high-throughput phenotypic screening Edinburgh Carragher, Neil
Decision making and mental capacity in MND Edinburgh Abrahams, Sharon
Understanding neuromuscular transmission failure in organophosphorus pesticide toxicity Edinburgh Dissanayake, Kosala
Synaptic pathology in ALS-FTD Edinburgh Grant, Seth
Energy metabolism in motor neuron diseases Edinburgh Faller, Kiterie
Molecular characterisation of underlying systemic pathologies in spinal muscular atrophy Glasgow Hunter, Gillian
Delineating the role of defects in the ubiquitin--proteasome system in MND Glasgow Kurz, Thimo
Genotype-Phenotype Characterisation of MND in Scotland Glasgow Leighton, Danielle
Investigating links between MND and RNA biology St Andrews Sleeman, Judith
Pathophysiological disease mechanisms underlying motor neuron dysfunction in MND St Andrews Miles, Gareth
ALS-FTD pathophysiology: treating the circuit behind the disease St Andrews Allodi, Ilary
Cognitive and behavioural impairment in Presymptomatic ALS and FTD University of Stirling McHutchison, Caroline
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