For academics: explore our research

The scientific details of our current research projects.

Project Name	Primary Location	Principal Investigator
Decision making and mental capacity in MND	Edinburgh	Abrahams, Sharon
ALS-FTD pathophysiology: treating the circuit behind the disease	St Andrews	Allodi, Ilary
New drugs that stabilise motor axons (UK Spinal Muscular Atrophy Consortium)	Edinburgh	Becker, Catherina
Neuromuscular junctions (NMJs) as therapeutic targets in MND	Aberdeen	Bewick, Guy
Advancing drug discovery through high-throughput phenotypic screening	Edinburgh	Carragher, Neil
Modelling MND using human induced pluripotent stem cells	Edinburgh	Chandran, Siddharthan
MND-SMART Clinical Trial	Edinburgh	Chandran, Siddharthan
Understanding neuromuscular transmission failure in organophosphorus pesticide toxicity	Edinburgh	Dissanayake, Kosala
Energy metabolism in motor neuron diseases	Edinburgh	Faller, Kiterie
Developing new therapies for motor neuron disease (SMA and ALS)	Edinburgh	Gillingwater, Tom
7T MRI Imaging in Patients with MND to identify Non-Invasive Disease Biomarkers of Disease.	Glasgow	Gorrie, George
Synaptic pathology in ALS-FTD	Edinburgh	Grant, Seth
Understanding the molecular pathogenesis of clinical heterogeneity in motor neuron disease	Aberdeen	Gregory, Jenna
Signaling pathways to degeneration and resilience	Edinburgh	Hardingham, Giles
High-resolution imaging of synaptic integrity in MND	Dundee	Henstridge, Chris
Molecular characterisation of underlying systemic pathologies in spinal muscular atrophy	Glasgow	Hunter, Gillian
Cellular and molecular anatomy of the human neuromuscular junction	Edinburgh	Jones, Ross
Delineating the role of defects in the ubiquitin--proteasome system in MND	Glasgow	Kurz, Thimo
Genotype-Phenotype Characterisation of MND in Scotland	Glasgow	Leighton, Danielle
Studying myelinated axon biology using zebrafish	Edinburgh	Lyons, David
Development of RAR ligands for the treatment of motor neuron disease	Aberdeen	McCaffery, Peter
Investigating the role of TDP-43 in ALS	Dundee	McGurk, Leeanne
Cognitive and behavioural impairment in Presymptomatic ALS and FTD	University of Stirling	McHutchison, Caroline
Pathophysiological disease mechanisms underlying motor neuron dysfunction in MND	St Andrews	Miles, Gareth
Identifying novel neuroprotective mechanisms in motor neuron disease	Edinburgh	Murray, Lyndsay
CARE-MND	Edinburgh	Pal, Suvankar
Cardiovascular and organ pathology in spinal muscular atrophy	Aberdeen	Parson, Simon
Understanding ALS with the Fly	Edinburgh	Pennetta, Giusy
Stem cell disease modelling to investigate mechanisms of selective vulnerability of motor neurons	Edinburgh	Selvaraj, Bhuvaneish T
Elucidating RNA metabolism changes underlying the progressive neural cell biology of ALS	Edinburgh	Sibley, Chris
The cell and molecular biology of neurodegenerative disease	Edinburgh	Skehel, Paul
Investigating links between MND and RNA biology	St Andrews	Sleeman, Judith
Edinburgh Brain Bank	Edinburgh	Smith, Colin